中国中医药信息杂志Issue(8)：56-58,3.DOI:10.3969/j.issn.1005-5304.2013.08.020
枣地安神丸质量标准研究
Study on Quality Standard of Zaodi Anshen Pills
摘要
Abstract
Objecfive To establish the quality standard of Zaodi Anshen Pills. Methods TLC method was used to identify Spinosae and Radix polygoni Multiflori. HPLC method was used to determine the schisandrin, deoxyschizandrin and schisandrin B. Eclipse XDB-C18 column (250 mm×4.6 mm, 5 µm) was adopted by gradient elution using MeOH-water solution as the mobile phase. The detection wavelength was at 254 nm, column temperature was at 40 ℃ and the flow rate was 1.0 mL/min. Results The TLC spots were clear without interference of the negative control. The linear ranges of schisandrin, deoxyschizandrin and schisandrin B were within 338-1690 ng (r 2=0.999 1), 128-640 ng (r 2=0.999 3) and 236-1180 ng (r 2=0.999 4), and the average recoveries were 99.2%, 99.0% and 98.9% respectively. Conclusion This method is accurate, reliable, specific and reproducible, and can be used for quality control of Zaodi Anshen Pills.关键词
枣地安神丸/质量标准/薄层色谱法/五味子醇甲/五味子甲素/五味子乙素/高效液相色谱法Key words
Zaodi Anshen Pills/quality standard/TLC/schisandrin/deoxyschizandrin/schisandrin B/HPLC分类
医药卫生引用本文复制引用
王智,王爽,许贵军,高菲..枣地安神丸质量标准研究[J].中国中医药信息杂志,2013,(8):56-58,3.基金项目
黑龙江省中医药管理局中医药科研项目(ZHY12-2062) （ZHY12-2062）
