中国中医药信息杂志2015，Vol.22Issue(11)：86-88,3.DOI:10.3969/j.issn.1005-5304.2015.11.024
复方沙塔干口服液质量标准研究
Study on Quality Standards for Compound Shatagan Oral Liquid
摘要
Abstract
Objective To establish the quality standards for compound Shatagan Oral Liquid. Methods Chuanxiong Rhizoma was identified by TLC. The content of ferulic acid was determined by HPLC. Separation was performed on a Diamonsil C18 column (4.6 mm × 250 mm, 5μm) with a mobile phase consisting of methanol-1% acetic acid solution in gradient elution (0-5 min, 35% methanol;5-8 min, 35%→23% methanol;8-22 min, 23% methanol) at 30℃;The flow rate was 1.0 mL/min;The injection volume was 5μL;The detection wavelength was 322 nm.Results Ferulic acid showed a good linear relationship in the range of 0.039 4-0.630 0μg (r=0.999 7,n=7). The average recovery was 98.22% and RSD was 2.62% (n=6).Conclusion The method is reliable, sensitive and with repeatability, which can be used as the quality control method for compound Shatagan Oral Liquid.关键词
复方沙塔干口服液/阿魏酸/高效液相色谱法/薄层色谱法/质量标准Key words
compound Shatagan Oral Liquid/ferulic acid/HPLC/TLC/quality standard分类
医药卫生引用本文复制引用
余双英,刘绣华,张凤,朴淑娟,陆文铨..复方沙塔干口服液质量标准研究[J].中国中医药信息杂志,2015,22(11):86-88,3.基金项目
军队中药口服液类特色制剂的质量标准研究(14ZJZ02-4) （14ZJZ02-4）
