中国卒中杂志Issue(4)：250-254,5.
大脑中动脉闭塞或狭窄缺血性卒中患者血液炎性标志物变化
Changes of Inflammatory Biomarkers in Ischemic Stroke Patients with Middle Cerebral Artery Occlusion or Stenosis
摘要
Abstract
Objective To analyze the risk factors and the changes of white blood cell(WBC), erythrocyte sedimentation rate(ESR) and high-sensitivity C-reactive protein(hs-CRP) in ischemic stroke patients with middle cerebral artery occlusion(MCAO) and stenosis. <br> Methods From January 2005 to January 2011, 262 unselected ischemic stroke patients who were admitted to Department of Neurology in Beijing Friendship Hospital were enrolled into our study. It included 98 patients with MCAO(MCAO group), 23 patients with 70%~99% stenosis in middle cerebral artery(MCA)(severe stenosis group), 60 patients with 50%~69% stenosis in MCA(moderate stenosis group), and 81 patients with less 50% stenosis in MCA(mild stenosis group). The risk factors and WBC, ESR and hs-CRP in 24 h after admission were compared among four groups. <br> Results The proportion of history of diabetes mellitus in the MCAO group, severe stenosis group and moderate stenosis group was significantly higher than that in the mild stenosis group(P=0.008, 0.044, 0.018), There were no significant differences in other risk factors among the four groups. WBC, ESR and hs-CRP levels in the MCAO group was significant higher than those in the mild stenosis group(P=0.005, 0.002, 0.001). The level of ESR in the severe stenosis group was also significantly higher than that in the mild stenosis group(P=0.026). <br> Conclusion WBC, ESR and hs-CRP levels elevated in stroke patients with occlusion and severe stenosis in MCA.关键词
大脑中动脉闭塞/白细胞/红细胞沉降率/超敏C反应蛋白Key words
Middle cerebral artery occlusion/White blood cell/Erythrocyte sedimentation rate/High-sensitivity C-reactive protein引用本文复制引用
邓丽,谢聃,张拥波,李继梅..大脑中动脉闭塞或狭窄缺血性卒中患者血液炎性标志物变化[J].中国卒中杂志,2013,(4):250-254,5.基金项目
北京市卫生系统高层次卫生技术人才培养计划项目资助(2009-3-07) （2009-3-07）
