中国卒中杂志Issue(8)：603-607,5.
动脉-动脉栓塞性缺血性卒中患者晨峰血压与颈动脉溃疡斑块的相关性研究
Association of Morning Blood Pressure Surge with Carotid Artery Plaque Ulceration in Ischemic Stroke Patients with Pathogenesis of Artery to Artery Embolism
程伟 1包艳娥 2聂莉 1李婉秋 1乔向亮 1程晓玲1
作者信息
- 1. 441300 随州湖北医药学院附属随州市中心医院神经内科
- 2. 湖北医药学院附属随州市中心医院心内科
- 折叠
摘要
Abstract
Objective To investigate the association of morning blood pressure surge (MBPS) with carotid artery plaque ulceration (CAPU) in ischemic stroke (IS) patients. Methods One hundred and twenty IS patients diagnosed with artery to artery embolism based on Chinese Ischemic Stroke Subclassiifcation (CISS) were enrolled in this study. MBPS was monitored by ambulatory blood pressure monitoring within 24 hours, and CAPU was examined by carotid ultrasonography. The association of MBPS with CAPU was evaluated by the Logistic regression model. Results The mean age of the total 120 IS patients was (62.6±12.8) years old, and 36.8% was female. Compared with the MBPS-group (n=72), the MBPS+group (n=48) did not have higher detection rate of CAPU (31.3%vs 30.6%, P=0.84). After separation of ipsilateral CAPU and contralateral CAPU, we found the detection rate was higher in MBPS+group than MBPS-group (27.1%vs 19.4%, P=0.008). The multivariate analysis showed that MBPS was associated with ipsilateral CAPU (odds ratio[OR], 1.42;95%conifdence interval[CI], 1.09~4.22) after adjusting for age and sex. The association still existed after further adjusting for other risk factors (OR 1.23;95%CI 1.02~3.46). Conclusion MBPS is associated with ipsilateral CAPU in the IS patients with pathogenesis of artery to artery embolism, which implies that higher MBPS may contribute to the fall of plaque that led to the occurrence of artery to artery embolism.关键词
晨峰血压/颈动脉溃疡斑块/缺血性卒中Key words
Morning blood pressure surge/Carotid artery plaque ulceration/Ischemic stroke引用本文复制引用
程伟,包艳娥,聂莉,李婉秋,乔向亮,程晓玲..动脉-动脉栓塞性缺血性卒中患者晨峰血压与颈动脉溃疡斑块的相关性研究[J].中国卒中杂志,2013,(8):603-607,5.
