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听神经瘤治疗策略和手术效果的研究--附594例报告

张治华 黄琦 汪照炎 吕静荣 贾欢 杨军 吴皓

中华耳科学杂志Issue(1):19-24,6.
中华耳科学杂志Issue(1):19-24,6.DOI:10.3969/j.issn.1672-2922.2013.01.005

听神经瘤治疗策略和手术效果的研究--附594例报告

Management Strategy and Surgical Outcomes in Acoustic Neuroma:A Report of 594 Cases

张治华 1黄琦 1汪照炎 1吕静荣 1贾欢 1杨军 1吴皓1

作者信息

  • 1. 上海交通大学医学院附属新华医院耳鼻咽喉头颈外科,上海交通大学耳科学研究所,上海 200092
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摘要

Abstract

Objective To report surgical outcomes and management strategies in acoustic neuroma. Methods Man⁃agement strategies and surgical outcomes in 594 patients with sporadic acoustic neuroma (461 surgical procedures) treated from January 2001 to December 2010 were retrospectively reviewed. Results The rate of intracanal/small, medium/moder⁃ately large and large/giant tumors was 25.6%, 55.1%and 19.3%respectively in the 594 cases. The rate of“wait and scan”, radiotherapy and surgery in this group was 25.3%, 6.9% and 77.6% respectively. Of the 461 surgeries, the rate of total, near-total and subtotal removal was 95.9%, 3.0%and 1.1%, respectively. The rate of intraoperative anatomical preserva⁃tion of the facial nerve (FN) was 94.4%. Short-term and long-term good FN function rates were 69.8%and 79.0%. The rate of hearing preservation and useful hearing were 41.4%and 23.4%. The mortality rate was 0.2%. The rates of lower cranial nerve palsy and cerebrospinal fluid leakage were 3.9%and 3.3%. Recurrence rate was 2.2%. Conclusions Surgical resec⁃tion is still the main management approach in acoustic neuroma, with satisfactory outcomes. The management strategy may be changed by early diagnosis of tumor.

关键词

听神经瘤/治疗策略/面神经/听力保留/并发症

Key words

Acoustic neuroma/management strategy/facial nerve/hearing preservation/complication

分类

医药卫生

引用本文复制引用

张治华,黄琦,汪照炎,吕静荣,贾欢,杨军,吴皓..听神经瘤治疗策略和手术效果的研究--附594例报告[J].中华耳科学杂志,2013,(1):19-24,6.

基金项目

本研究受国家自然科学基金(30973307,2010-2012)资助 (30973307,2010-2012)

中华耳科学杂志

OA北大核心CSCDCSTPCD

1672-2922

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