浙江医学Issue(1)：38-40,3.
A 型肉毒毒素颅周肌肉注射治疗慢性偏头痛临床观察
Pericranial intramuscular injection of botulinum toxin type A for treatment of chronic migraine
王晋荣 1祝海燕 2徐艳1
作者信息
- 1. 324000 衢州，浙江中医药大学附属衢州中心医院神经内科
- 2. 324000 衢州，浙江中医药大学附属衢州中心医院临床药学科
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and adverse effects of botulinum toxin type A (BTX-A) in treatment of chronic migraine. Methods One hundred and one patients with chronic migraine were randomly divided into BTX-A group and control group. The headache impact test (HIT-6) scores were measured at 0, 1, 2, 3 and 6 months after treatment, and the mi-graine disability assessment scale (MIDAS) scores were measured at 0, 3 and 6 months after treatment. HIT-6 scores, MIDAS scores and the use of analgesics were compared between the two groups. Results There were significant differences in HIT-6 scores (P<0.05) and MIDAS scores (P<0.01) between the two groups. The doses of analgesics in BTX-A group were reduced significantly (P<0.01). The therapeutic effect of BTX-A lasted for 6 months, and no obvious adverse effects were observed. Conclusion Pericranial intramuscular injection of BTX-A is an effective and safe therapeutic method for chronic migraine.关键词
慢性偏头痛/A 型肉毒毒素/治疗Key words
Chronic migraine/Botulinum toxin type A/Treatment引用本文复制引用
王晋荣,祝海燕,徐艳..A 型肉毒毒素颅周肌肉注射治疗慢性偏头痛临床观察[J].浙江医学,2013,(1):38-40,3.
