浙江医学Issue(2)：108-110,3.
意外胆囊癌组织层粘连蛋白受体的表达与肿瘤转移的关系研究
Expression of laminin receptor and its relation to metastasis in patients with unexpected gallbladder carcinoma
宋政炜 1倪全法 1蒋达峰 1费建国 1秦红波1
作者信息
- 1. 314000 嘉兴学院附属第二医院肝胆外科
- 折叠
摘要
Abstract
Objective To investigate the expression of laminin receptor (LN-R) and its relation to clinicopathological fea-tures of unexpected gal bladder carcinoma (UCG). Methods The expression of LN-R was detected by immunohistochemical assay in 49 patients with UCG; its relation to clinicopathological features of UCG patients was analyzed. Results The positive rate of LN-R expression was 71.4% in 49 cases. The expression of LN-R was correlated with the clinical stage of carcinoma. The metastasis rate of UGC accounted for 59.2% (29/49) after surgery; 68.6% (24/35) patients with LN-R expression had metas-tasis compared to 35.7% (5/14) in those without LN-R expression (P<0.05). Conclusion The expression of LN-R may predict postoperative metastasis in patients with UCG and suggests the necessity of secondary radical resection.关键词
意外胆囊癌/肿瘤转移/层粘连蛋白受体Key words
Unexpected gallbladder carcinoma/Neoplasm metastasis/Laminin receptor引用本文复制引用
宋政炜,倪全法,蒋达峰,费建国,秦红波..意外胆囊癌组织层粘连蛋白受体的表达与肿瘤转移的关系研究[J].浙江医学,2013,(2):108-110,3.
