浙江医学Issue(3)：183-185,3.
RhD阴性女性妊娠期意外抗体筛选的回顾性研究
陈舒 1洪小珍 1许先国 1蓝小飞 1马开荣 1刘瑛 1何吉 1吕杭军1
作者信息
- 1. 310006 杭州，浙江省血液中心卫生部血液安全重点实验室
- 折叠
摘要
Abstract
Objective To screen unexpected antibody in RhD-negative pregnant women. Methods Total 376 Rh-neg-ative pregnant women were analyzed retrospectively. The screening of unexpected antibody and detection of antibody titer were conducted by salt medium, polyamine and antiglobulin methods. Results Unexpected antibodies were found in 33 cases ac-counting for 8.8%of total (33/376), including 24 cases with anti-D (72.7%), 2 anti-D combined anti-C (6.1%), 2 anti-E (6.1%), 1 anti-Fyb(3.0%), 1 anti-P1 (3.0%)and 1anti-M (3.0%);and the antibodies specificity was not identified in 2 cases(6.1%). Seventy eight out of 376 cases were screened more than twice. During the fol ow-up among 14 positive cases 8 had increased antibodies titer, 2 had decreased titer and 4 had no change;while among 64 negative cases unexpected antibodies turned to positive in 3 cases and 61 cases remained negative. Conclusion Unexpected antibodies exist in serum of RhD-negative pregnant women, which indicates that regularly screening of unexpected antibody wil help to adopt intervention strategy promptly for the RhD-negative pregnant women.关键词
RhD阴性/妊娠期女性/意外抗体筛查Key words
Rh-negative/Pregnant women/Screening of unexpected antibodies引用本文复制引用
陈舒,洪小珍,许先国,蓝小飞,马开荣,刘瑛,何吉,吕杭军..RhD阴性女性妊娠期意外抗体筛选的回顾性研究[J].浙江医学,2013,(3):183-185,3.
