浙江医学Issue(8)：634-636,3.
贴敷式局部亚低温治疗对急性重症脑出血疗效及免疫功能的影响观察
Local subhypothermia in treatment of acute severe cerebral hemorrhage and its effect on immunological function
摘要
Abstract
Objective To evaluate the efficacy of local subhypothermia with adhesive dressing for severe brain hemor-rhage and its effect on immunological function of patients. Methods Sixty patients with acute severe cerebral hemorrhage were randomized into 2 groups: subhypothermia group (n=30) and control group (n=30). Al patients were given conventional therapy;while patients in subhypothermia group received additional subhypothermia therapy with local adhesive dressing. The volume of the cerebral edema or infarction, NIH Stroke Scale and the activity of daily living score (Barthel Index)were evaluated to judge disable level between zgroups. The CD4+, CD8+ cel s in peripheral blood were measured. The fatality rate and infection rate were observed and compared between two groups. Results The volume of edema or cerebral infarct was lower in subhypothermia group than that in control groups after 14d treatment (P<0.05). There was no significant difference in baseline NIHSS and BI scores between two groups (P >0.05), the scores were improved more markedly in subhypothermia group than those in control group after 30 and 180d treatment (P<0.05). Conclusion The local subhypothermia therapy is safe and effective for patients with acute cerebral hemorrhage.关键词
贴敷式局部亚低温/脑出血/CD4+T细胞Key words
Adhesive local dressing and mild hypothermia/Cerebral hemorrhage/T lymphocyte subsets CD4+引用本文复制引用
黄雪融,张顺开,林瑞声,刘凌云,王小同..贴敷式局部亚低温治疗对急性重症脑出血疗效及免疫功能的影响观察[J].浙江医学,2013,(8):634-636,3.基金项目
温州市卫生局医药卫生科学研究资助项目（05030）；温州市重大课题项目 （）
