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严重创伤患者D-二聚体水平的变化及意义

何革 吴川峰 陈春悦

浙江医学Issue(8):645-646,660,3.
浙江医学Issue(8):645-646,660,3.

严重创伤患者D-二聚体水平的变化及意义

Plasma D-dimmer levels in patients with severe trauma and its clinical significance

何革 1吴川峰 2陈春悦1

作者信息

  • 1. 310003 杭州,浙江省中西医结合医院外科,中心实验室
  • 2. 浙江中医药大学第二临床学院
  • 折叠

摘要

Abstract

Objective To evaluate the clinical significance of plasma D-dimmer levels in patients with severe trauma. Methods Four hundred and eleven patients with severe trauma (trauma group) and 400 healthy subjects (control group) were in-cluded in this study. The plasma D-dimmer levels were measured by col oidal gold immune infiltration method in controls and in trauma patients at 24 and 96h after surgery respectively. Results The D-dimmer positive rate and plasma levels at 24 and 96h after surgery in trauma patients were significantly higher than those of normal controls (P<0.01). Traumatic deep vein thrombosis (TDVT) developed in 38 patients (9.2%), whose 24 and 96 h D-dimmer levels were significantly higher than that of control group (both P<0.01) and 373 trauma patients without TDVT developed (P<0.05 or 0.01). The rate of high D-dimmer levels at 24h in TDVT patients was significantly higher than that in non-TDVT trauma patients (65.8%, 1.9%, P<0.01). Conclusion High plasma D-dimmer level may indicate the development of traumatic deep vein thrombosis in patients with severe trauma.

关键词

创伤/创伤性深静脉血栓/D-二聚体

Key words

Trauma/Traumatic deep venous thrombosis/D-dimmer

引用本文复制引用

何革,吴川峰,陈春悦..严重创伤患者D-二聚体水平的变化及意义[J].浙江医学,2013,(8):645-646,660,3.

浙江医学

OACSTPCD

1006-2785

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