浙江医学Issue(9)：762-764,3.
腹腔镜胃癌根治术患者外周血CK19mRNA的变化及意义
Expression of CK19 mRNA in patients with gastric cancer undergoing laparoscopic radical resection and its clinical significance
摘要
Abstract
Objective To investigate the expression of CK19 mRNA in patients with gastric cancer undergoing laparo-scopic radical resection and its significance. Methods The expression of peripheral blood CK19mRNA was detected by fluo-rescence quantitative polymerase chain reaction (FQ-PCR) technology in patients with gastric cancer undergoing laparoscopic radical resection(laparoscopy group, n=14) or laparotomy resection(laparotomy group, n=37). Results The operation time in la-paroscopy group was shorter than that in laparotomy group (P<0.01), while there were no significant differences in e intraopera-tive blood loss and number of removed lymph node between two groups (P>0.05). There was no difference in expression of CK19mRNA before and after operation in laparoscopy group (P>0.05), while there was statistical y significant in laparotomy group (P<0.05). The rate of positive CK19mRNA expression in laparotomy group after operation was higher than that in laparo-scopic group (P<0.05). Conclusion Compared to laparotomy, laparoscopic radical resection of gastric cancer can reduce the positive rate of CK19mRNA expression in peripheral blood and the risk of tumor micrometastasis after operation.关键词
腹腔镜/胃癌/微转移/细胞角蛋白19 mRNAKey words
Gastric cancer/Micrometastasis/Laparoscopy/CK19 mRNA引用本文复制引用
倪开元,徐鲲杰,洪晓明,汪东杰..腹腔镜胃癌根治术患者外周血CK19mRNA的变化及意义[J].浙江医学,2013,(9):762-764,3.
