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急性肺栓塞患者血浆脑钠肽与右心功能的关系及其预后评估价值

周忠良 季巧英 马旭 金凯频

浙江医学Issue(15):1432-1434,3.
浙江医学Issue(15):1432-1434,3.

急性肺栓塞患者血浆脑钠肽与右心功能的关系及其预后评估价值

BNP levels in patients with acute pulmonary embolism are correlated with right ventricular function

周忠良 1季巧英 1马旭 1金凯频1

作者信息

  • 1. 322100 东阳市人民医院血管外科
  • 折叠

摘要

Abstract

Objective To investigate the correlation of plasma B type natriuretic peptide (BNP) level with right ventricular function in patients with acute pulmonary embolism. Methods Plasma BNP level was measured by ELISA in 44 patients with a-cute pulmonary embolism. According to the results of echocardiography,the patients were classified as normal right ventricular function group and right ventricular dysfunction group.The correlation of plasma BNP level with ventricular function and the inci-dence of adverse events was analyzed. Results BNP level in right ventricular dysfunction group were significantly higher than that in normal right ventricular function group (2 352.5±1 987.8 vs 349.9±299.4 pg/ml, P<0.01).The incidence of adverse out-come events in the BNP- positive group was higher than that in BNP- negative group (69.2%vs 10.0%, P<0.05).The survival rate in the BNP- negative group was higher than that in BNP- positive group (χ²=6.554, P<0.05). Conclusion Plasma BNP lev-els are correlated with right ventricular function in patients with acute pulmonary embolism, which may be of prognostic value for acute pulmonary embolism.

关键词

脑钠肽/急性肺栓塞/右心功能

Key words

Brain natriuretic peptide/Acute pulmonary embolism/Right ventricular function

引用本文复制引用

周忠良,季巧英,马旭,金凯频..急性肺栓塞患者血浆脑钠肽与右心功能的关系及其预后评估价值[J].浙江医学,2013,(15):1432-1434,3.

浙江医学

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