肿瘤药学Issue(2):130-132,142,4.DOI:10.3969/j.issn.2095-1264.2013.031
食管癌根治术后纵膈淋巴结转移三维适形小野放疗临床观察
The Clinical Observation of Small Field Three Dimensional Conformal Radiation Therapy (SF-3DCRT) for Patients with Mediastinal Lymph Node Metastasis after Radical Resection of Esophageal Carcinoma
陈意标 1张汉雄 1张坚 1俞海东 1邓国明 2洪珊 3薛祥兴4
作者信息
- 1. 梅州市人民医院放疗二科,广东 梅州,514031
- 2. 梅州市人民医院肿瘤外一科,广东 梅州,514031
- 3. 梅州市人民医院医院信息中心,广东 梅州,514031
- 4. 梅州市人民医院内科,广东 梅州,514031
- 折叠
摘要
Abstract
Objective To investigate the significance and curative effect of three dimensional conformal radiation therapy (3D-CRT) in mediastinal lymph node metastasis after radical resection of esophageal carcinoma. Methods A retrospec-tive analysis was done by 45 patients with mediastinal lymph node metastasis after radical resection of esophageal carcinoma. They were treated by conventional fractionated SF-3DCRT, the GTV (gross tumor volume) prescription dose is 64 Gy and the CTV (clinical target volume) prescription dose is 50 Gy, CTV is 1~1.5 cm Outside the scope of GTV. No prophylactic irradiation in the other site which is not metastasis. Results CT examinations were taken after 3 months’radiotherapy. Ac-cording to RECIST(Response Evaluation Criteria in Solid Tumors), the total effective rate is 73.3%, the complete remission rate is 33.3%, the median survival time is 16.7 months, toxicity and side effect are not obvious. Conclusion 3DCRT is rec-ommended for the patients with Mediastinal Lymph Node Metastasis after Radical Resection of Esophageal Carcinoma.关键词
食管癌/纵隔淋巴结转移/三维适形放疗/小野Key words
Esophageal carcinoma/Mediastinal lymph node metastasis/Three dimensional conformal radiation therapy/Small field分类
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陈意标,张汉雄,张坚,俞海东,邓国明,洪珊,薛祥兴..食管癌根治术后纵膈淋巴结转移三维适形小野放疗临床观察[J].肿瘤药学,2013,(2):130-132,142,4.