肿瘤药学Issue(3)：188-191,4.DOI:10.3969/j.issn.2095-1264.2013.045
衡阳地区HIV阳性妇女宫颈HPV感染情况研究★
Human Papillomavirus Infection of Cervix Uteri in HIV-positive Women from Hengyang★
摘要
Abstract
Objective To study the infection of Human papilloma virus (HPV) among HIV-positive women from Hengyang, and to provide a scientific basis for the HPV epidemiological research on HIV-positive groups. Methods A total of 4576 women were tested for sero-antibody of HIV by ELISA and immuno-colloidal golden method. The positive speci-mens detected by both methods were further sent out to confirm. Meanwhile 4576 cervical tissue specimens were examined for HPV by PCR and membrane hybridization method. Results The rate of HIV infection was 0.83% in 4 576 women, and that of HPV was 21.02%. The HPV-positive rate of 60.53% in HIV-positive group had statistical difference from that of 20.69% in HIV-negative group (χ2=36.02, P<0.005). Among 962 HPV-positive women, the rate of mixed HPV infection in HIV-positive group was 56.52%, but that in HIV-negative group was 20.98%; there were statistical difference between the two groups (χ2=16.62, P<0.005). Conclusion The rate of HPV infection of cervix Uteri in HIV-positive women was high, and high risk HPV and multiple HPV infection happened commonly, both of which indicated that HPV infection had close relation with HIV-positive patients.关键词
人乳头瘤病毒/人类免疫缺陷病毒/感染/宫颈癌Key words
Human papillomavirus/Human immunodeficiency virus/Infection/Cervix Uteri分类
医药卫生引用本文复制引用
谢小平,唐双阳,刘安元,李乐..衡阳地区HIV阳性妇女宫颈HPV感染情况研究★[J].肿瘤药学,2013,(3):188-191,4.基金项目
湖南省教育厅项目资助(12C0342)；湖南省卫生厅项目资助（B2011-043）。 （12C0342）
