摘要
Abstract
Objective:To investigate the effects of different doses of Remifentanil and Propofol to anesthesia in patients’ cardiovascular response during pneumoperitoneum.Method:150 cases of laparoscopic surgery patients were randomly selected by computer and divided into A,B,C three groups,50 cases in each group.A,B and C three groups of patients were given Remifentanil 0.2,0.4 and 0.6 μg/(kg·min), and combined with Propofol anesthesia.Three groups of patients’ mean arterial pressure(MAP) and heart rate(HR) were detected during these steps, pre-intubation 10 min(T0),before establishing pneumoperitoneum(T1),after establishing pneumoperitoneum 5 min(T2) and during establishing pneumoperitoneum 10 min(T3).Result:Three groups of patients’ MAP at T0 all decreased significantly than T1’s MAP(P<0.05).Compared to Group B and C,Group A decreased significantly,the difference of which had statistical meaning (P<0.05).MAP of T2 all significantly increased than T1’s MAP, Group A increased observably than Group B and C,the difference of which had statistical meaning(P<0.05).The MAP of T3 and T2 had no significant difference(P>0.05).HR of T1 was significantly lower than T0’s HR(P<0.05).The decreased degree of Group A was significantly lower than those in Group B and C, the difference of which had statistical meaning(P<0.05).HR of T2 rebounded more than that of T1.Group A’s rebounded degree was significantly higher than Group B and C,the difference of which had statistical meaning(P<0.05).HR of T3 and T2 had no significant difference(P>0.05).Conclusion:Low-dose Remifentanil and Propofol to anesthesia has more impact on cardiovascular response during pneumoperitoneum.A moderate-and-high doses of Remifentanil and Propofol to anesthesia can effectively reduce the response of cardiovascular patients during pneumoperitoneum,which has better effects.关键词
瑞芬太尼/丙泊酚/腹腔镜/心血管反应Key words
Remifentanil/Propofol/Laparoscope/Cardiovascular response分类
医药卫生
