中医药学报Issue(5)：31-35,5.
22种常见抗肿瘤中草药的抗氧化活性研究
Antioxidant Activity of 22 Chinese Herbal Medicines for Anti-cancer
摘要
Abstract
Objective:In this study ,22 Chinese herbal medicines for anti -cancer were developed for the study of its an-tioxidant activity .Methods:The antioxidant activities of samples were evaluated by DPPH method;phenols , flavonoids contents and total reducing power were estimated by using the Folin -Ciocalteu reagent , aluminum salt colorimetric method and ferric-reducing antioxidant power assay ( FRAP) .Results:The results confirmed that 90 .09%of the medi-cine had characterized the antioxidant activity with more than 50%, which included eight kinds of plant materials such as Rhizoma Curcumae , Rhizoma Polygoni Cuspidati , Wild Skullcaps , Radix Paeoniae Alba , Fern , Salviamiltiorrhiza , Radix Dipsaci Asperoidis , Curcuma longa demonstrated better antioxidant activity ( activity >90%) .Wild Skullcaps demonstrated the best antioxidant activity with the lowest IC 50 value of 0.05g/L, the highest phenolic and flavonoid con-tents of 5240μg/L and 83210μg/L.Conclusion:Each sample for anti -cancer has a strong antioxidant activity except for the Coix seed and Poria , which confirms natural antioxidant and antitumor effect has a certain correlation , but its mechanism needs further research .In this study , it is possible to find antioxidants and antioxidant -based anticancer drugs develop from broad anti -tumor natural resources providing an experimental basis .关键词
中草药/抗氧化活性/DPPH法/FRAP法/总酚含量/黄酮含量Key words
Chinese medicinal herb/Antioxidant activity/DPPH/FRAP/Phenolic content/Flavonoid content分类
医药卫生引用本文复制引用
张新国,刘英娟,曹心张,张春生,匡彦蓓..22种常见抗肿瘤中草药的抗氧化活性研究[J].中医药学报,2015,(5):31-35,5.基金项目
国家自然科学基金 （）
