医药导报2015，Vol.34Issue(12)：1637-1639,3.DOI:10.3870/j.issn.1004-0781.2015.12.022
左旋紫草素转化工艺
Transforming Process of Shikonin
摘要
Abstract
Objective To investigate the optimal condition for transforming alkanna tinctoria pigment into shikonin. Methods Transformation rate of shikonin served as index. Transformation temperature, time, ratio of 2% NaOH to alkanna tinctoria pigment (v/w) was optimized. Results With ratio of 2% NaOH to alkanna tinctoria pigment being 4.5 mL·mg-1, temperature 35℃ and the reaction time 4 h, the transformation rate reached the highest, and the average transformation rate was 64.86%. Conclusion This method is easy and simple, and suitable for industrialized production.关键词
紫草总色素/左旋紫草素/正交实验Key words
Alkanna tinctoria pigment/Shikonin/Orthogonal design分类
医药卫生引用本文复制引用
周健,郭瑞霞,王汝兴,赵桂琴..左旋紫草素转化工艺[J].医药导报,2015,34(12):1637-1639,3.基金项目
河北省高等学校科学研究计划(Q2012096) （Q2012096）
河北省研究生创新资助项目(Z0000004) （Z0000004）
