姚海木 1付新 1孙同文 2张晓娟 2沈德良 1张金盈 1李凌1
作者信息
- 1. 郑州大学第一附属医院心内科，河南郑州 450052
- 2. 郑州大学第一附属医院综合ICU，河南郑州 450052
- 折叠
摘要
Abstract
ObjectiveTo investigate the long-term prognosis and factors associated with clinical events of patients with coronary artery disease(CAD)treated with domestic drug-eluting stent.Methods All patients with CAD undergone percutaneous coronary intervention(PCI)successfully and,at least,implanted one domestic drug-eluting stent in the first affiliated hospital of Zhengzhou university from July 2009 to December 2010 were included in the analysis.Exclusion criteria were patients implanted with bare metal stent or different stents(domestic and imported DES)simultaneously.Clinical,laboratory,angiographic and procedural data were collected.The follow-up was conducted by outpatient interviews,reviewing hospital records and via telephone interviews and adverse cardiac events were recorded.Comparisons among continuous variables were made by using one-way ANOVA.Categorical data were tested usingx2 test or the Fisher exact test.Multivariate Logistic regression analysis was performed to identify independent predictors of prognosis.All statistical analyses.Results There were a total of 1228 patients enrolled in the analysis and a follow up after 29 months was obtained in 1136 patients(92.5%),Follow-up time was (29.1±5.9) months. Patients with urgent PCI accounted for 2.5% of cases,patients with non-urgent PCI amounted to 18.4%,patients with NSTE-ACS consisted of 66% and patients with stable angina constituted 13%.The highest mortality during the hospitalization was noted within the urgent PCI group(3.4%).During follow up, death occurred in 5.7%,re-myocardial infarction in 2.6%,revascularization in 6.6%,in-stent restenosis in 3.7% and MACCE(death/myocardial infarction/stroke)in 9.94%.Multiple regression model showed that independent risk factors for MACCE during the follow up were:older age,heart rate,decreased left ventricular ejection fraction,multivessel disease,and restenostic lesions. Conclusion In the real life PCI practice STEMI patients undergone urgent PCI have the worst hospital and long-term prognosis.Well recognized risk factors for death in patients with CAD are still of great importance in negative prognosis of patients undergoing PCI.关键词
长期预后/冠心病/经皮冠状动脉介入术/药物洗脱支架Key words
Long-term prognosis/Coronary artery disease/Percutaneous coronary intervention/Drug-eluting stent分类
医药卫生
