中国医药科学Issue(19)：166-168,3.
血清胱抑素C、血C反应蛋白、尿微量白蛋白联合检测早期诊断糖尿病肾病的意义
Significance of combined detection of serum cystatin C,serum C-reactive protein and microalbuminuria in early diagnosis of diabetic nephropathy
秦蕾 1杨旭 2张亚文1
作者信息
- 1. 吉林油田总医院检验科，吉林松原 138000
- 2. 吉林油田总医院内分泌科，吉林松原 138000
- 折叠
摘要
Abstract
Objective To explore significance of combined detection of serum cystatin C,serum C-reactive protein and microalbuminuria in early diagnosis of diabetic nephropathy.Methods72 patients with early diabetic nephropathy who were admitted to our hospital from June 2014 to May 2015 were selected as the observation group.60 healthy people who received physical examination in our hospital in the same period were selected as the control group.Cys-C,CRP and mALB levels of two groups were detected.Differences of Cys-C,CRP and mALB levels of two groups and of different genders,positive rate of single detection and combined detection of three indexes were compared.Results Cys-C,CRP and mALB levels of the observation group were significantly higher than those of the control group and the difference was statistically significant(P<0.05).The positive rate of combined detection of three indexes was significantly higher than that of single detection of three indexes and the difference was statistically significant(P<0.05).Differences in Cys-C,CRP and mALB levels of male patients with early diabetic nephropathy and female patients with early diabetic nephropathy had no statistical significance(P>0.05).Conclusion Cys-C, CRP and mALB levels of patients with diabetic nephropathy are significantly higher and Cys-C,CRP and mALB levels of different genderss has no obvious differences.Combined detection three indexes of positive rate is significantly increased which is worthy of promotion and application in clinic as a detective method to predicate early diabetic nephropathy.关键词
糖尿病肾病/胱抑素C/C反应蛋白/微量白蛋白Key words
Diabetic nephropathy/Cystatin C/C-reactive protein/Albumin分类
医药卫生引用本文复制引用
秦蕾,杨旭,张亚文..血清胱抑素C、血C反应蛋白、尿微量白蛋白联合检测早期诊断糖尿病肾病的意义[J].中国医药科学,2015,(19):166-168,3.
