长春中医药大学学报Issue(6)：1186-1188,3.DOI:10.13463/j.cnki.cczyy.2015.06.032
真武汤合桃红四物汤对阳虚血瘀型慢性收缩性心力衰竭患者血浆 BNP 的影响
Zhenwu Decoction and Taohongsiwu Decoction on yang deficiency and blood stasis of blood BNp in patients with chronic congestive heart failure
摘要
Abstract
objective To observe effect of Zhenwu Decoction and Taohongsiwu Decoction on Yang deficiency and blood stasis of average BNP in patients with chronic congestive heart failure. Methods The 80 patients with yang de-ficiency and blood stasis type of heart failure were selected to test the average BNP,they were randomly divided into the study group and the control group with 40 cases in each. The control group was treated with routine western medi-cine,the study group was treated with Zhenwu Decoction and Taohongsiwu Decoction on the basis of the control group. The two groups took 8 weeks of continuous treatment. The patients’informations,included curative effect,left ventricular ejection fraction(LVEF),brain natriuretic peptide(BNP),had been collected and observed before and after treatment. Results Before the treatment,the average BNP of the control group was(544. 97 ± 213. 26)pg /mL,the average BNP of the study group was(545. 46 ± 211. 19)pg / mL. There was no difference of the average BNP level in the comparison between the two groups(P > 0. 05). Before the treatment,the LVEF of the control group was 44. 58% ± 5. 66% ,the LVEF of the the study group was 43. 38% ± 6. 61% . There was no difference of the LVEF in the comparison between the two groups(P > 0. 05). The Cardiac function in total effective rate of the control group and the study group were 76. 92% ,94. 87% ,the study group showed the better efficacy than the con-trol group(P < 0. 05). This study showed that the average BNP of the two groups of patients decreased after treat-ment,with significant differences( P < 0. 01). On improving of the decreased level of BNP,the treatment group showed the better efficacy than the control group(P < 0. 05). This study showed that LVEF of the two groups of pa-tients increased after treatment,with significant differences(P < 0. 05);But there was no difference of the increased level of LVEF in the comparison between the two groups . Conclusion Zhenwu Decoction and Taohongsiwu Decoc-tion can improve the clinical symptoms and signs of patients of chronic congestive heart failure with Yang deficiency and blood stasis,and can increase the LVEF,decrease the average BNP.关键词
B 型钠尿肽/慢性心力衰竭/阳虚血瘀/真武汤/桃红四物汤Key words
brain natriuretic peptide/chronic congestive heart failure/yang deficiency blood stasis/Zhenwu Decoc-tion/Taohongsiwu Decoction分类
医药卫生引用本文复制引用
肖晓,陈兆善..真武汤合桃红四物汤对阳虚血瘀型慢性收缩性心力衰竭患者血浆 BNP 的影响[J].长春中医药大学学报,2015,(6):1186-1188,3.基金项目
上海交通大学医学院附属新华医院崇明分院科研基金项目“真武汤合桃红四物汤对阳虚血瘀型慢性收缩性心力衰竭血 BNP 的影响”（M201308）。 （）
