广西医学2015，Vol.37Issue(10)：1400-1402,1406,4.DOI:10.11675/j.issn.0253-4304.2015.10.07
宫腔灌注粒细胞集落刺激因子对薄型子宫内膜患者冻融胚胎移植周期中子宫内膜厚度的影响
Effect of intrauterine perfusion with granulcoyte colony-stimulating factor on endometr ial thickness in patients with thin endometrium during frozen embryo tranfser cycle
黄晖 1姜小玲 1吴洪波 1李洁 1蒋嫔娥 1李柳铭1
作者信息
- 1. 广西医科大学第一附属医院生殖医学研究中心,南宁市 530021
- 折叠
摘要
Abstract
Objective To explore the variations of endometrial thickness(EMT) and morphology after intrauterine perfusion with granulocyte colony-stimulating factor(GC-SF) in patients with thin endometrium during the frozen embryo transfer (FET)cycle.Methods Thirty patients with thin endometrium who planed to receive FET were enrolled .The patients were treated with intrauterine perfusion with G-CSFduring endometrial preparation.The EMT and endometrial morphology were detected on the 13th(D13),16th(D16) and 19 th(D19) day of the perfusion cycle,and were compared with those at the corresponding time points of the last cycle.Results EMT on the D13 and D16 of the perfusion cycle was a little thicker than that of the last cycle,but there was no significant difference(P>0.05).And EMT on the D19 of the perfusion cycle was significantly thicker than that of the last cycle(P<0.05).During the perfusion cycle,EMT on the D19 was significantly thicker than that on the D13,but EMT on the D16 showed no significant difference compared to that on the D13 or D19(P>0.0)5. During the perfusion cycle, there was no significant difference in the endometrial morphology among D 13, D16 and D19 ( P >0.05 ) . Conclusion For patients with thin endometrium undergoing endometrial preparation during FET cycle ,intrauterine perfusion with GC-SF can improve the EMT,but has no significant effect on the improvement of endometrial morphology .关键词
薄型子宫内膜/冻融胚胎移植/粒细胞集落刺激因子/宫腔灌注/子宫内膜厚度/子宫内膜形态Key words
Thin endometrium/Frozen embryo transfer/Granulocyte colony-stimulating factor/Intrauterine perfusion/Endometrial thickness/Endometrial morphology分类
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黄晖,姜小玲,吴洪波,李洁,蒋嫔娥,李柳铭..宫腔灌注粒细胞集落刺激因子对薄型子宫内膜患者冻融胚胎移植周期中子宫内膜厚度的影响[J].广西医学,2015,37(10):1400-1402,1406,4.
