吉林大学学报（理学版）Issue(6)：1316-1320,5.DOI:10.13413/j.cnki.jdxblxb.2015.06.46
氨基化的介孔二氧化硅纳米材料与 pDNA 作用
Amino-functionalized Mesoporous Silica Nanoparticles Interacting with pDNA
摘要
Abstract
This work evaluated the adsorption and protection capacities of amino-functionalized mesoporous silica nanoparticles (Am-MSNs)for pDNA (PEGFP-N3).The in vitro biocompatibilities of Am-MSNs to A549 and Hela cells were also tested,respectively.The results reveal that the Am-MSNs exhibit good adsorption capacity for PEGFP-N3.Moreover,the material can also protect PEGFP-N3 from enzymatic degradation completely.In addition,the sample presents high in vitro biocompatibilities to HeLa and A549 cells.关键词
氨基化介孔二氧化硅纳米材料/质粒 DNA/吸附/保护/生物相容性Key words
amino-functionalized mesoporous silica nanoparticle (Am-MSNs)/pDNA/adsorption/protection/biocompatibility分类
化学化工引用本文复制引用
郑昆,杨红,葛雅琨,隋新,温刚,张元新..氨基化的介孔二氧化硅纳米材料与 pDNA 作用[J].吉林大学学报（理学版）,2015,(6):1316-1320,5.基金项目
国家自然科学基金(批准号:50573030) （批准号:50573030）
