检验医学与临床Issue(24)：3657-3659,3.DOI:10.3969/j.issn.1672-9455.2015.24.018
血清淀粉样蛋白A检测在冠心病诊断中的意义
Significance of the detection of serum amyloid A in the diagnosis of coronary heart disease
赵锐 1李艳 1戴雯 1许淑文 1周方元1
作者信息
- 1. 武汉大学人民医院检验医学中心 430060
- 折叠
摘要
Abstract
Objective To detect the level of serum amyloid A (SAA) in the patients with coronary heart dis‐ease (CHD) ,and to investigate the significance of SAA in the diagnosis of stable angina (SA) ,unstable angina (UA) ,and acute myocardial infarction (AMI) .Methods 149 cases of CHD patients (CHD group ,including 42 cases of SA ,54 cases of UA ,and 53 cases of AMI) and 102 cases of healthy individuals (normal control group) were se‐lected .All of the CHD patients were diagnosed by coronary arteriongraphy .The levels of ALT ,AST ,TBIL ,BUN ,Cr and UA were detected by SIEMENS Advia2400 automatic biochemical analyzer ,and SAA was detected by immuno‐fluorescence assay .Results Comparing with normal control group ,the SAA level of CHD group increased signifi‐cantly (P<0 .05) .And the SAA level of AMI patients was significantly higher than those of SA and UA patients , with statistical difference (P<0 .05) .Conclusion SAA might play a role in the occurrence or development of CHD , which could be an observational biomarker of CHD patient′s condition ,and help to prevent and diagnose CHD .关键词
血清淀粉样蛋白A/冠心病/诊断Key words
serum amyloid A/coronary heart disease/diagnosis引用本文复制引用
赵锐,李艳,戴雯,许淑文,周方元..血清淀粉样蛋白A检测在冠心病诊断中的意义[J].检验医学与临床,2015,(24):3657-3659,3.
