摘要
Abstract
Objective To explore the clinical study of combined application of Ambroxol Hydrochloride Injec‐tion and phentolamine injection in the treatment of severe pneumonia in children .Methods 108 cases of children with severe pneumonia were randomly divided into two groups ,all were given conventional symptomatic treatment ,such as oxygen ,anti infection ,antiviral ,antipyretic ,sedative ,cough and asthma ,and study group were given intravenous infu‐sion of ambroxol hydrochloride and phentolamine injection ,the main symptoms of the contrastive analysis of two groups of curative effect ,improve the changes the main indicators of time .Results the two groups after treatment the total effective rate of study group 92 .59% was significantly higher than the control group 70 .37% (P< 0 .05) ;the study group defervescence ,wet rales disappearance ,failure elimination ,asthma ,hospitalization time were signifi‐cantly lower than those of the control group (P< 0 .05) ;the two groups after treatment of high sensitivity C reactive protein (hs‐CRP) and procalcitonin (PCT ) ,tumor necrosis factor‐α(TNF‐α) were significantly decreased ( P < 0 . 05) ,the research group decreased than that of the control group (P< 0 .05) ,the difference was statistically signifi‐cant .Conclusion on the basis of conventional symptomatic treatment of children with severe pneumonia ,given ambr‐oxol combined with phentolamine treatment ,can improve the efficacy effectively ,accelerate the improvement of clini‐cal symptoms ,decrease the inflammatory reaction .关键词
氨溴索/酚妥拉明/重症肺炎/儿童Key words
ambroxol hydrochloride/phentolamine/severe pneumonia/children
