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蒙药查格德日丸对偏头痛大鼠脑和血中NO和NOS的影响

武小兰 佟强 胡玉荣

内蒙古民族大学学报(自然科学版)Issue(6):515-517,3.
内蒙古民族大学学报(自然科学版)Issue(6):515-517,3.

蒙药查格德日丸对偏头痛大鼠脑和血中NO和NOS的影响

Effects of Chagederi Pills on NO and NOS in Plasma and Brain of Rats with Migraine

武小兰 1佟强 2胡玉荣2

作者信息

  • 1. 内蒙古民族大学蒙医药学院,内蒙古通辽028000
  • 2. 内蒙古民族大学附属医院,内蒙古通辽028000
  • 折叠

摘要

Abstract

Objective: To study the effect of Chagederi pills on NO and NOS in plasma and brain of rats with mi-graine. Methods:The migraine model was induced with the SD rats by subcutaneous injection of nitroglycerin. After the model induced for 30min, the experimental group was given Chagederi pills by lavage administration;the blank group and the model group were given the equal volume of distilled water. After administration 4h, the levels of NO and NOS in rats brain and blood were detected by spectral method. Results:The NO and NOS content in migraine rats' plasma and brain in middle dose and high dose Chagederi pills groups were decreased. Conclusion:Chagederi pills play a role in the treatment of migraine possibly by reducing the content of NO and NOS in brain and blood.

关键词

查格德日丸/偏头痛/一氧化氮/一氧化氮合酶

Key words

Chagederi pill/Migraine/NO/NOS

分类

医药卫生

引用本文复制引用

武小兰,佟强,胡玉荣..蒙药查格德日丸对偏头痛大鼠脑和血中NO和NOS的影响[J].内蒙古民族大学学报(自然科学版),2015,(6):515-517,3.

基金项目

内蒙古自治区高等学校科学研究项目 ()

内蒙古民族大学学报(自然科学版)

1671-0185

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