山东医药Issue(46)：11-13,3.DOI:10.3969/j.issn.1002-266X.2015.46.004
粤西地区328例肾功能代偿期 IgA 肾病患者并发高尿酸血症的影响因素分析
Risk factors for IgA nephropathy complicated with hyperuricemia in renal function compensatory phase of 328 cases of patients from western part of Guangdong
摘要
Abstract
Objective To analyze the risk factors for IgA nephropathy complicated with hyperuricemia in renal func -tion compensatory phase of patients in western part of Guangdong province .Methods The clinical and pathological data of 328 patients with IgA nephropathy were selected to analyze the risk factors of hyperuricemia .Results The incident of hy-peruricemia in patients with IgA nephropathy was 38 .4% ( 126/328 ) .Univariate regression analysis suggested that the age, serum creatinine, blood urea nitrogen, serum triglyceride, serum total cholesterol, glomerulus sclerosis score, glomer-ular injury integral , tubular-interstitial injury score , renal small vessel injury score and Lee's grade might be related to the IgA nephropathy patients complicated with hyperuricemia (all P<0.05).Multivariate regression analysis showed that the serum triglyceride and renal small vessel injury score >2 were related with the occurrence of hyperuricemia in patients with IgA nephropathy (all P<0.05).Conclusion The hypertriglyceridemia and renal small vessel injury score >2 are inde-pendent risk factors for patients with IgA nephropathy in renal function compensatory phase from western part of Guangdong province .关键词
粤西地区/IgA肾病/高尿酸血症/影响因素Key words
western part of Guangdong province/IgA nephropathy/hyperuricemia/risk factor分类
医药卫生引用本文复制引用
路杰,陈秋华,刘华锋,潘庆军..粤西地区328例肾功能代偿期 IgA 肾病患者并发高尿酸血症的影响因素分析[J].山东医药,2015,(46):11-13,3.基金项目
国家自然科学基金资助项目（81202346）；广东省湛江市科技攻关项目（2010C3105017）。 （）
