世界中医药Issue(11)：1802-1805,4.DOI:10.3969/j.issn.1673-7202.2015.11.044
中医药对抑郁动物模型海马结构影响的研究进展
Progress of Research on the Effects of Chinese Medicine on Hippocampal Formation in Depression Animal Models
摘要
Abstract
Depression is a common psychological disorder characterized by persistent depressive feelings,and its incidence in-creased year by year and its recurrence rate is high.In recent years,the research on the etiology of depression has made certain progresses.Hippocampus formation is closely related to emotion and cognition response.In recent years,the relationship between the morphology and ultrastructure of hippocampus and the changes of ultrastructure and depression have drawn increasing attention. Hippocampal neurons atrophy,variation and death of the hippocampus have been found in animals with depression,which were ac-companied by regeneration dysfunction.Besides,there are more and more studies have confirmed that the variation and low activity of the hippocampus are the pathogenesises of depression.In treating depression,Chinese medicine has the advantage of with sel-dom side effects and excelled in syndrome differentiation.At present,the mechanism of anti depression of Chinese medicine is not clear,especially about its effect on the morphology and ultrastructure of the hippocam,which were mainly based on animal experi-ments.This article analyzed literature in recent years and discussed the effects of Chinese medicine on depression from following aspects:the impacts of traditional Chinese medicine compound,Chinese medicine,herbal extracts,acupuncture,electro acupunc-ture on the structure of the hippocampus.关键词
抑郁症/海马结构/综述Key words
Depression/Hippocampal formation/Summary分类
医药卫生引用本文复制引用
李鸿娜,颜红..中医药对抑郁动物模型海马结构影响的研究进展[J].世界中医药,2015,(11):1802-1805,4.基金项目
青年科学基金项目“从致炎细胞因子对下丘脑的影响探讨复方丹参方干预心肌梗死预后的机制” （）
