武警医学2015，Vol.26Issue(12)：1213-1215,1220,4.
对烧伤患者检测血清降钙素原和尿肾损伤分子1 的临床意义
Meaning of serum PCT and urine KIM-1 detection for urine kidney damage in patients with different degree burns
刘媛媛 1郑天亮 2韩忠学 1周婷1
作者信息
- 1. 110034 沈阳,武警辽宁总队医院检验科
- 2. 100089 北京,武警总部门诊部
- 折叠
摘要
Abstract
Objective To study the meaning of serum PCT and urine KIM-1 detection for urine kidney damage in patients with different degree burns .Methods 123 burn patients admitted from January -December 2013 in this hospital were divided intomild , medium and severe burn groups .40 subjects andergoing physical examination during the same period in this hospital were selected as controls.Generally signs (body temperature, heart rate, breathing), CRP, BUN, Cys-C, PCT and KIM -1 levels were compared be-tween the two groups .Results Compared with healthy control group , mild-to-severe burn group had no significant difference in terms of body temperature, heart rate and respiration (P>0.05).Mild-to-severe burn group, compared to healthy group, had statistically significant difference in WBC levels (11.5 ±2.7,12.7 ±3.3,17.9 ±5.6,P<0.05), but had no remarkable difference compared with mild-to-moderate burn group that the severe burn group and mild-to-moderate burn group havd statistically significant difference .The CRP level in mild-to-severe burn group had obvious difference compared with healthy group (P<0.05) while no obvious difference a-mong the three burn groups (P>0.05).As to BUN measurement, only severe burn group had difference with other groups (P<0.05).The difference in the Cys-C levels in moderate-to-severe burn group compared with healthy group had statistically significant differcace (P<0.05).All differences in terms in PCT and KIM-1 levels of burn groups compared with healthy group had statistically significant difference .And the differences in PCT and KIM-1 levels among different burn groups ( mild-to-moderate , moderate-to-se-vere, mild-to-severe) had statistically significant difference (P<0.05).Conclusions The serum PCT and KIM-1 can be used in dif-ferent degree burn patients with sepsis in the early detection , which is of great significance .关键词
血清降钙素原/尿肾损伤分子1/烧伤Key words
serum PCT/urine KIM-1/burns分类
临床医学引用本文复制引用
刘媛媛,郑天亮,韩忠学,周婷..对烧伤患者检测血清降钙素原和尿肾损伤分子1 的临床意义[J].武警医学,2015,26(12):1213-1215,1220,4.
