中国组织工程研究Issue(47)：7575-7582,8.DOI:10.3969/j.issn.2095-4344.2015.47.006
应用浓缩生长因子行上颌窦内提升后种植体周围骨变化
Application of concentrated growth factor in maxillary sinus lift：variation in peri-implant bone levels
摘要
Abstract
BACKGROUND:Many experiments and clinical studies have reported that venous blood, absorbable colagen sponge and rich fibrin clot, without the use of bone graft material, can al promote new bone formation; therefore, whether only transplanting concentrated growth factor in the maxilary sinus lift could effectively promote bone regeneration? OBJECTIVE: To conduct the maxilary sinus lift with concentrated growth factor as the graft material, and to observe the peri-implant bone level change. METHODS: Totaly 26 patients were involved, including 14 males and 12 females, aged 35-73 years. Maxilary sinus lift was conducted and autologous concentrated growth factor was taken as the graft material. Astra Tech implants were implanted simultaneously. Patients were divided into 6-12 months, 13-18 months and > 18 months groups according to the folow-up time. Patients were divided into≤ 5 mm, 5-7 mm, and≥ 7 mm groups according to the preoperative alveolar bone height. Patients were divided into≤ 2 mm, 2.0-3.0 mm, and≥3 mm groups according to the postoperative maxilary sinus lift height. The survival rate of implants and marginal bone level changes were observed during the folow-up. RESULTS AND CONCLUSION: Totaly 44 implants were implanted, of which 43 implants were considered as successful repair during the 6-18 months of postoperative folow-up. The survival rate of implants was 98%. There were no significant differences in the changes of mesial, distal and middle marginal bone levels between different folow-up time groups. The maxilary sinus lift with transplantation of concentrated growth factor resulted in a good osseointegration within 6-18 months post-operation. In addition, no significant differences were found in the changes of mesial, distal and middle marginal bone levels between different residual alveolar bone height groups, as wel as between different maxilary sinus lift height groups. It showed that the residual alveolar bone height and maxilary sinus lifting height had no significant effect on the peri-implant bone formation. Briefly, these findings demonstrate that the maxilary sinus lift with concentrated growth factor transplantation can result in a high survival rate of implants that are simultaneous implanted, and the alveolar bone around the implant is stable. But the long-term effect needs further observation.关键词
生物材料/口腔生物材料/浓缩生长因子纤维蛋白膜/上颌窦内提升/同期种植/边缘骨水平分类
医药卫生引用本文复制引用
黄娜,吴锋,李平,刘子平,林炬,唐尤超,王远勤..应用浓缩生长因子行上颌窦内提升后种植体周围骨变化[J].中国组织工程研究,2015,(47):7575-7582,8.基金项目
2014惠州市科技计划项目(2014Y112)@@@@the Science and Technology Plan Project of Huizhou City in 2014, No.2014Y112 （2014Y112）
