现代医药卫生2015，Vol.31Issue(23)：3544-3545,3548,3.DOI:10.3969/j.issn.1009-5519.2015.23.006
右美托咪定在下肢深静脉血栓介入治疗中的应用
Application of dexmedetomidine in interventional therapy of lower extremity deep vein thrombosis
张全云 1张晓群 1孟凡珍1
作者信息
- 1. 连云港市第二人民医院麻醉科,江苏 222000
- 折叠
摘要
Abstract
Objective To evaluate the application of dexmedetomidine in the interventional therapy of lower extremity deep vein thrombosis (DVT). Methods Forty patients with elective lower extremity DVT interventional therapy in our hospital from January 2013 to July 2015 were selected and randomly assigned into the dexmedetomidine group and the control group ,20 cases in each group. The dexmedetomidine group was intravenously dripped with load dose of dexmedetomidine 1 μg/kg for more than 10 min before surgery,then dexmedetomidine 0.5 μg/(kg·h) was maintained via pumping during surgery until the end of surgery;whereas the equal volume of normal saline was given in the control group C. The VAS score and Ramsay sedation score were adopted to evaluate the analgesia and sedation effects. The adverse reactions such as intraoperative hypertension ,bradycar-dia and hyoxemia were also recorded. Results Compared with the control group,the VAS scores at T2-5 in the dexmedetomidine group were decreased,while the Ramsay scores were increased,intraoperative bradycardia was increased and occurrence rate of hypertension was decreased,the differences were statistically significant(P<0.05). Compared with T1,the VAS scores at T5 in the control group was decreased,while the Ramsay scores were increased,the differences were statistical different(P<0.05). Conclu-sion Dexmedetomidine has better analgesic and sedative effects and can maintain the hemodynamic stability during the lower extremity DVT interventional therapy.关键词
静脉血栓形成/下肢/血液供给/输注,静脉内/安定镇痛/血压Key words
Venous thrombosis/Lower extremity/blood supply/Infusions/intravenous/Neuroleptanalgesia/Blood pressure引用本文复制引用
张全云,张晓群,孟凡珍..右美托咪定在下肢深静脉血栓介入治疗中的应用[J].现代医药卫生,2015,31(23):3544-3545,3548,3.
