摘要
Abstract
Objective To investigate the effect of mifepristone and misoprostol combined with early uterine curettage in early pregnancy artificial abortion operation. Methods 659 early pregnant women in our hospital from January 2014 to January 2015 were selected as the research subjects and randomly divided into the observation group (386 cases) and the control group(273 cases). The two groups were given the medication abortion scheme of mifepristone and misoprostol. The observation group was per-formed the routine uterine curettage at 3 h after taking misoprostol , while whether conducting the uterine curettage in the control group was determined according to the follow up situation. Contemporaneous 256 early pregnant women requiring painless artifi-cial abortion were selected as the painless artificial abortion group. The rate of complete abortion ,total cost,vaginal bleeding amount,bleeding time and pain situation caused by curettage operation were compared among 3 groups. Results The complete abortion rate in the observation group was 100%,the amount of vaginal bleeding and bleeding time were obviously reduced com-pared with the control group,the differences were statistically significant(P<0.05). The needing total cost had no statistical differ-ence between the observation group and the control group (P>0.05);the total cost in the painless artificial abortion group was high er than that in the observation group and the control group,the difference was statistically significant(P<005). The occurrence rates of mild pain and severe pain in the observation group were lower than those in the control group with statistical difference (P<0.05). Conclusion Mifepristone and misoprostol combined with early uterine curettage can increase the complete abortion rate ,reduce intraoperative bleeding and bleeding time ,moreover the needing cost is reduced ,which is suitable for popularization in rural areas.关键词
出血/出血时间/流产,人工/方法/刮宫术/米非司酮/米索前列醇Key words
Hemorrhage/Bleeding time/Abortion/induced/methods/Dilatation and curettage/Mifepristone/Misoprostol
