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他汀类药物对内皮祖细胞作用的研究进展

沈根 张顺 叶红华

新医学Issue(12):789-793,5.
新医学Issue(12):789-793,5.DOI:10.3969/j.issn.0253-9802.2015.12.001

他汀类药物对内皮祖细胞作用的研究进展

Research progress of the effect of statin therapy on endothelial progenitor cells

沈根 1张顺 2叶红华2

作者信息

  • 1. 315010 宁波,宁波大学医学院
  • 2. 315010 宁波,宁波市第二医院
  • 折叠

摘要

Abstract

Endothelial progenitor cells (EPC)are immature bone marrow-derived cells that have the ability to differentiate into mature endothelial cells.EPC are involved in the angiogenesis after birth and the healing of endothelial cells of injured vessels.Several studies have demonstrated that the quantity and function of circulating EPC are negatively correlated with the risk factors of cardiovascular diseases.Statin agents has been proven to increase the quantity and enhance the function of EPC,which may contribute to clinical benefits in the treat-ment of cardiovascular diseases.Here,we reviewed the research progress of the effect of statin therapy upon EPC.

关键词

内皮祖细胞/他汀类药物/心血管疾病

Key words

Endothelial progenitor cell/Statins/Cardiovascular disease

引用本文复制引用

沈根,张顺,叶红华..他汀类药物对内皮祖细胞作用的研究进展[J].新医学,2015,(12):789-793,5.

基金项目

浙江省医药卫生科技计划 ()

新医学

OACSTPCD

0253-9802

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