哈尔滨商业大学学报(自然科学版)2015,Vol.31Issue(6):678-681,4.
蓬子菜中活性成分DXG大鼠血浆蛋白结合率测定
Determination of plasma protein binding rate of DXG from Galium verum L.in rat
摘要
Abstract
To determinate the protein-bound fraction of serum of DXG from Galium verum L.Equilibrium dialysis was used to determine the in vitro binding rate of DXG to rat plasma. A HPLC method for determination of DXG dialysated inside solution and outer solution was established.Plasma protein binding rate of DXG in different concentration was 29.39%, 29.85%, 32.94%, respectively.The methods were specific and sensitive, which can be used in determination of biological specimen.The plasma protein binding of DXG in rats re-veals a low binding and has no concentration dependence.关键词
蓬子菜/DXG/血浆蛋白结合率/平衡透析法Key words
Galium verum L./DXG/plasma protein binding rate/equilibrium dialysis分类
医药卫生引用本文复制引用
崔明宇,孙志伟,李艳凤,马英丽..蓬子菜中活性成分DXG大鼠血浆蛋白结合率测定[J].哈尔滨商业大学学报(自然科学版),2015,31(6):678-681,4.基金项目
国家自然科学基金项目(201281274034) (201281274034)
黑龙江省教育厅科学技术研究项目(12531625) (12531625)