摘要
Abstract
Objective To compare the drug resistance ofAcinetobacter baumannii (AB) between intensive care units(ICU) and non-ICU departments,in order to provide evidence for control of nosocomial infection.Methods All the isolated AB strains were identified by VITEK-2 COMPACT system.Antimicrobial susceptibility test were conducted by disc diffusion test,and drug resistance rates were calculated by nosocomial infection real-time monitoring and early warning system.Results (1) A total of 2797 pathogenic microorganism were detected,and 385 strains of AB were cultured and isolated,which made up 13.76% of total isolated sample.230 of which were isolated from ICU,and 155 from non-ICU departments.(2) Sputum was the main source where AB were isolated (289,75.1%),followed by cerebrospinal fluid (22,5.7%) and blood sample(19,4.9%),etc.(3) Drug resistant strains of AB were isolated higher in ICU than non-ICU departments,and the difference was statistically significant (χ2=8.863,P=0.003).(4) Drug sensitivity test results showed: strains of AB that isolated from ICU had higher drug resistance for imipenem,meropenem,piperacillin and amikacin than non-ICU departments,and the difference were statistically significant (P<0.05).Conclusions The isolation rate and drug resistance rate of AB in ICU is higher than that in non-ICU departments.Surveillance for drug resistance should be reinforced,and rational use of antimicrobial agents is critical to prevent the prevalence of drug resistant AB in nosocomial infection.关键词
鲍曼不动杆菌/耐药性/医院感染Key words
Acinetobacter baumannii/drug resistance/nosocomial infection分类
医药卫生
