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中药复方参五地口服液对小鼠的急性毒性试验

胡宏伟 李仁阁 张成虎

现代农业科技Issue(23):275,278,2.
现代农业科技Issue(23):275,278,2.

中药复方参五地口服液对小鼠的急性毒性试验

Acute Toxicity Test of Chinese Medicine Compound Shenwudi Oral Liquid in Mice

胡宏伟 1李仁阁 1张成虎1

作者信息

  • 1. 甘肃省兰州市畜牧兽医研究所,甘肃兰州 730050
  • 折叠

摘要

Abstract

In order to evaluate the safety and ascertain the toxicity of the Chinese medicine Compound Shenwudi Oral Liquid,the experiment of acute toxicity and the determination of LD50 of the shenwudi oral liquid were conducted in mice with different doses.The results showed that the LD50 of the Shenwudi Oral Liquid was 22.44 g/kg and its 95%confidence was 19.756~25.485 g/kg.The mortality rate of mice with drug dose increased and the increase of body mass in mice with drug dose significantly slower after the medication for seven days.Results indicated that food belongs to actually non-toxic clinical drugs was safe.

关键词

中药/复方参五地口服液/小鼠/急性毒性

Key words

Chinese medicine/Compound Shenwudi Oral Liquid/mice/acute toxicity

分类

畜牧业

引用本文复制引用

胡宏伟,李仁阁,张成虎..中药复方参五地口服液对小鼠的急性毒性试验[J].现代农业科技,2015,(23):275,278,2.

基金项目

甘肃省农业生物技术研究与应用开发项目(GNCX-2014-1). (GNCX-2014-1)

现代农业科技

1007-5739

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