湖南中医药大学学报2016，Vol.36Issue(1)：66-69,4.DOI:10.3969/j.issn.1674-070X.2016.01.017
长沙市重性精神疾病社区药物治疗的安全性研究
Study of Drug Safety on Severe Mental Illness in Changsha Community
摘要
Abstract
Objective To evaluate and analyze the medication safety of severe mental illness in Changsha community. Methods In community drug for the treatment of 365 cases of severe mental illness patients for object, through three times extrapyramidal (RSESE), abnormal involuntary movement (AIMS), adverse reactions (UKU) scale and laboratory examination, electrocardiogram (ECG) examination were carried on the statistical analysis to discuss treatment medication safety. Results Three RSESE score values have no statistical significance; The difference between the first and third times AIMS score was statistically significant (P<0.05); The first time UKU score compared the second and third time value was statistically significant (P<0.05); The blood routine examination between first and third time, blood glucose between first and second or third time, blood lipid between first or second with the third time, renal function between first and second time were statistical significance (P<0.05). Three times of liver function, hormone, ECG ratio have no statistical significance. The extrapyramidal adverse reactions were major with tremor, elbow stiffness, fixed posture; abnormal involuntary movement adverse reactions were major with upper facial, lip weeks; psychiatric adverse reactions were major with weakness, drowsiness, attention to fall. Conclusions Drug treatment for severe mental illness community was with stability for adverse reactions evaluation and high safety. We should regularly monitor and subsequent visit to drug extrapyramidal side effects, biochemical, blood picture, ECG abnormalities, in order to reduce the occurrence of adverse reactions.关键词
重性精神病患者/社区卫生服务/药物安全性/锥体外系副反应/异常不自主运动/精神性不良反应Key words
severe mental patients/community health service/drug safety/extrapyramidal system side reaction/abnormal involuntary movement/spiritual adverse effect分类
中医学引用本文复制引用
钟周,周甲龙,葛小平,王民主,柳春旺,唐江萍,程小芸,胡志希..长沙市重性精神疾病社区药物治疗的安全性研究[J].湖南中医药大学学报,2016,36(1):66-69,4.基金项目
民生科技支撑资金专项(K1207050-31). （K1207050-31）
