按摩与康复医学Issue(1)：11-13,14,4.
体外压力刺激对血管内皮细胞不同整合素亚基表达变化影响的研究
Study on the Effect of Pressure Stimulation in Vitro on the Expreesion Change of Different Integrin Subunit in Vascular Endothelial Cells
摘要
Abstract
Objective:To investigate the influence of massage pressure stimulation on different integrin subunit in vascular endothelial cells, in order to provide some experimental evidence and theory basis for the non-nerve signal transduction mechanism of the therapeutical effect of massage. Methods: Divided samples of vascular endothelial cells in vitro into blank control group (0kPa pressure stimulation group), 100kPa group and 200kPa group, stimulated by corresponding strength of static pressure, and observed the content change of Integrinβ1,β3,α1,α2,α3,αv that at the sur-face of vascular endothelial cell membrane. Results:The Integrinβ1,β3,α1,α2,α3,αv expression quantity of 100kPa and 200 kPa group were all more than those of blank control group (P<0.05), while the Integrinβ3expression quantity were both less than that of blank control group (P<0.05). Conclu-sion:In the process of stimulating massage pressure stimulation, the expression change of the integrin subunit which mediates mechanical signals in vascular endothelial cell membranes of acupoint has revealed the non-nerve signal transduction mechanism of the conduction of massage pressure stimulation signal on the vascular endothelial cells in a certain degree.关键词
推拿/压力刺激/血管内皮细胞/整合素亚基/非机械信号传导Key words
massag/pressure stimulation/vascular endothelial cell/integrin subunit/non-nerve signal transduction分类
医药卫生引用本文复制引用
胡铁汉,江瑜,陈波,陈磊,罗明鸿..体外压力刺激对血管内皮细胞不同整合素亚基表达变化影响的研究[J].按摩与康复医学,2016,(1):11-13,14,4.基金项目
贵州省高层次人才科研条件特助经费项目，编号TZJF-2011年-29号；贵州省科学技术基金，编号黔科合J字【2011】2304号；国家自然科学基金项目，编号30801490 （）
