Abstract
Objective:To investigate the bacterial distribution and drug sensitivity characteristics of chronic suppurative sinusi-tis.Methods:This study collected nasal secretions of 89 cases chronic suppurative sinusitis patients before operation,and nasal secre-tions were culture in medium.Disk diffusion method (Kirby-Bauer,K-B)was used for drug sensitivity test.Sensitivity of bacteria strain to cefazolin,ceftazidime,cefepime,imipenem,meropenem,vancomycin,cefoperazone Shubatan,ciprofloxacin and other anti-biotics were analyzed.Results:After the submission of purulent secretion specimens of nasal meatus in 89 cases chronic suppurative si-nusitis patients with sticky,we found that 80 of the patients were detected bacteria.Exclusion of Streptococcus /yellow Neisseria nasal flora,the positive rate was 89.89% (80 /89).80 patients were detected in 82 strains of bacteria,a total of 15 species,of which 1 case of nasal meatus sticky purulent secretion specimens there were 2 strains of bacteria.15 kinds of Staphylococcus aureus were detec-ted bacteria,Escherichia coli,Pseudomonas,Staphylococcus aureus,Enterobacter aerogenes,5 kinds of bacteria occupy the top 5,re-spectively,accounted for 18.29%,14.63%,14.63%,13.41 % and 10.98%.Drug sensitivity test of Staphylococcus aureus showed that all of the Staphylococcus aureus was sensitive to vancomycin,the sensitivity was 100%;the sensitivity of cefazolin,ceftazidime, cefepime,imipenem,meropenem,cefoperazone sulbactam,ciprofloxacin and other antibiotics were 0%.All the Staphylococcus epi-dermidis were sensitive to imipenem,meropenem,vancomycin,cefoperazone sulbactam,the sensitivity was 100%;followed by cefazo-lin,the sensitivity was 83.33%,and to ceftazidime,cefepime,ciprofloxacin sensitive,were all below 30%.Escherichia coli,Pseudo-monas aeruginosa and Enterobacter aerogenes and other gram negative bacteria were sensitive to imipenem,meropenem,the sensitivity was 100%.Conclusion:The bacterial infection in patients with chronic suppurative sinusitis pathogens,including Staphylococcus epi-dermidis,Staphylococcus aureus,Escherichia coli,Pseudomonas,Enterobacter aerogenes,bacterial culture positive to vancomycin,imi-penem,meropenem,cefoperazone Shubatan,cefazolin and antimicrobial susceptibility,and so on.The antimicrobial spectrum of change should be closely monitored in antimicrobial treatment in order to adjust the medication.关键词
慢性化脓性鼻窦炎/菌种/抗生素/敏感率Key words
Chronic suppurative sinusitis/Bacteria/Antibiotics/Sensitivity分类
医药卫生
