重庆医学Issue(35)：4940-4942,3.DOI:10.3969/j.issn.1671-8348.2015.35.013
糖尿病罹患胰腺癌相关临床特征分析
Related clinical characteristics of diabetes patients suffering from pancreatic cancer
摘要
Abstract
Objective To observe and analyze clinical characteristics of diabetes patients suffering from pancreatic cancer . Methods We recruited 107 cases of pancreatic cancer(66 without diabetes and 41 with diabetes) and 100 diabetes patients without pancreatic pancreas as control .Patients′ demographic information ,degree of tumor differentiation ,serum markers etc .were com‐pared in order to find out the relevant clinical features of diabetes patients suffering from pancreatic cancer .Results (1)Patients with pancreatic cancer mostly were middle‐aged males .55 .1% of them suffering from dysglycemia ,18(16 .8% ) and 41(38 .3% ) of whom had impaired fasting glucose and diabetes ,respectively .(2)Compared with their without diabetes counterparts ,pancreatic cancer with diabetes were more prone to be asymptomatic and weight loss(P< 0 .05) .(3)Compared with their without diabetes counterparts ,pancreatic cancer with diabetes had significantly higher levels of fasting blood glucose(FBG) andγ‐glutamyltranspep‐tidase(γ‐GT)(P<0 .05) .(4)When compared with diabetes control ,pancreatic cancer with diabetes were older and shorter duration and lower body mass index(BMI)(P<0 .05) .They were more prone to weight loss(P<0 .05) .Moreover ,serum CA19‐9 and CEA levels in them were significantly higher than those in the diabetes control(P<0 .05) .Conclusion Older age ,shorter duration ,low BMI are all risk factors for diabetes patients to develop pancreatic cancer .Being asymptomatic and weight loss are their clinical characteristics .CA19‐9 and CEA are both sensitive serum markers to detect pancreatic cancer patients with diabetes .关键词
糖尿病/胰腺肿瘤/癌胚抗原Key words
diabetes mellitus/pancreatic neoplasms/carcinoembrgonic antigen分类
医药卫生引用本文复制引用
陈晶波,金刚,周颖奇,宋彬,宋博,黄勤..糖尿病罹患胰腺癌相关临床特征分析[J].重庆医学,2015,(35):4940-4942,3.基金项目
国家自然科学基金资助项目（30871198；81272665）。 （）
