核化学与放射化学Issue(6):385-392,8.DOI:10.7538/hhx.2015.37.06.0385
硝基咪唑类 PET 肿瘤乏氧显像剂的研究总结和展望
Progress of Tumor Hypoxia Imaging Agents Containing Nitroimidazole for Positron Emission Tomography
于倩 1王振光 1陈成成 1刘思敏 1石彬1
作者信息
- 1. 青岛大学附属医院 PET/CT 中心,山东 青岛 266000
- 折叠
摘要
Abstract
Hypoxia imaging agents can selectively accumulate in hypoxic tissues or cells. With the advance of PET imaging technique,tumor hypoxia imaging for PET has great clini-cal value for guiding tumor therapy,evaluating therapeutic efficacy and estimating progno-sis.1 8 F-FMISO is the widely studied PET tumor hypoxia imaging agent containing nitroimid-azole,but it still has some disadvantages.Up to now,more and more novel PET tumor hypoxia imaging agents containing nitroimidazole are under investigation.This review briefly introduced some the research progress of tumor hypoxia imaging agents containing nitroimid-azole for PET.关键词
肿瘤乏氧/PET/硝基咪唑类乏氧显像剂Key words
tumor hypoxia/PET/nitroimidazole hypoxia imaging分类
医药卫生引用本文复制引用
于倩,王振光,陈成成,刘思敏,石彬..硝基咪唑类 PET 肿瘤乏氧显像剂的研究总结和展望[J].核化学与放射化学,2015,(6):385-392,8.