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硝基咪唑类 PET 肿瘤乏氧显像剂的研究总结和展望

于倩 王振光 陈成成 刘思敏 石彬

核化学与放射化学Issue(6):385-392,8.
核化学与放射化学Issue(6):385-392,8.DOI:10.7538/hhx.2015.37.06.0385

硝基咪唑类 PET 肿瘤乏氧显像剂的研究总结和展望

Progress of Tumor Hypoxia Imaging Agents Containing Nitroimidazole for Positron Emission Tomography

于倩 1王振光 1陈成成 1刘思敏 1石彬1

作者信息

  • 1. 青岛大学附属医院 PET/CT 中心,山东 青岛 266000
  • 折叠

摘要

Abstract

Hypoxia imaging agents can selectively accumulate in hypoxic tissues or cells. With the advance of PET imaging technique,tumor hypoxia imaging for PET has great clini-cal value for guiding tumor therapy,evaluating therapeutic efficacy and estimating progno-sis.1 8 F-FMISO is the widely studied PET tumor hypoxia imaging agent containing nitroimid-azole,but it still has some disadvantages.Up to now,more and more novel PET tumor hypoxia imaging agents containing nitroimidazole are under investigation.This review briefly introduced some the research progress of tumor hypoxia imaging agents containing nitroimid-azole for PET.

关键词

肿瘤乏氧/PET/硝基咪唑类乏氧显像剂

Key words

tumor hypoxia/PET/nitroimidazole hypoxia imaging

分类

医药卫生

引用本文复制引用

于倩,王振光,陈成成,刘思敏,石彬..硝基咪唑类 PET 肿瘤乏氧显像剂的研究总结和展望[J].核化学与放射化学,2015,(6):385-392,8.

核化学与放射化学

OA北大核心CSCDCSTPCD

0253-9950

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