中国健康心理学杂志Issue(1):13-16,17,5.DOI:10.13342/j.cnki.cjhp.2016.01.003
认知控制任务下精神分裂症患者健康亲属大脑激活模式的元分析
Meta Analysis of Brain Activity under Cognitive Control Tasks in Relatives of Patients with Schizophrenia
彭晓玲1
作者信息
- 1. 中国.广州儿童孤独症康复研究中心 广东广州 510540
- 折叠
摘要
Abstract
Objective:To investigate the brain activity patterns in healthy relatives of patients with schizophrenia under cognitive control tasks .Methods :Firstly ,we systematic searched the literatures using functional magnet reso-nance imaging(fMRI)to explore cognitive control tasks related brain activation patterns in healthy relatives of pa-tients with schizophrenia ;Then ,we extracted peak coordinates and converted them into the Talairch space .Results:Compared with healthy controls ,under cognitive control tasks ,healthy relatives of patients with schizophrenia showed decreased brain activity pattern in left insular ,and left cingulated gyrus ,and increased activation in left supe-rior frontal gyrus and left precentral gyrus (P<0 0.5) .Conclusion:The brain activity intrigued by cognitive tasks may be potential endphenotypes for schizophrenia .关键词
认知控制/功能磁共振/元分析/精神分裂症亲属Key words
Cognitive control/fMRI/Meta-analysis/Relatives of patients with schizophrenia分类
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彭晓玲..认知控制任务下精神分裂症患者健康亲属大脑激活模式的元分析[J].中国健康心理学杂志,2016,(1):13-16,17,5.