检验医学与临床2016,Vol.13Issue(2):179-180,183,3.DOI:10.3969/j.issn.1672-9455.2016.02.012
卵泡抑素样蛋白-1在川崎病诊断及冠状动脉损害中的作用
Role of follistatin-like protein-1 in Kawasaki disease diagnosis and its coronary arterial injury
摘要
Abstract
Objective To investigate the correlation between serum levels of follistatin-like protein-1 (FSTL-1) with Kawasaki disease (KD) and its coronary arterial injury .Methods 48 patients with KD were selected as the KD group and divided into the KD disease complicating coronary arterial injury group (4 cases) and the KD disease without complicating coronary arterial injury group(44 cases) .Contemporaneous 20 healthy children were selected as the control group .Serum FSTL-1 levels were measured by ELISA in each group .Results Serum FSTL-1 level in the KD patients was elevated as compared with the control group ,the difference was statistically significant (P<0 .05) . Serum FSTL-1 level in the KD patients complicating coronary arterial injury was significantly higher than that in the KD patients without complicating coronary arterial injury ,the difference was statistically significant(P<0 .05) .Con-clusion There is certain correlation between serum FSTL-1 level with KD ,which has possibility for the application in diagnosing KD related coronary arterial injury .关键词
川崎病/卵泡抑素样蛋白-1/冠状动脉损害Key words
Kawasaki disease/follistatin-like protein-1/coronary arterial injury引用本文复制引用
陈艳玲,李小琳,张莉,彭建明,官燕飞,袁斌,黄绍芬..卵泡抑素样蛋白-1在川崎病诊断及冠状动脉损害中的作用[J].检验医学与临床,2016,13(2):179-180,183,3.基金项目
广东省中山市科技计划项目(2014A1FC011). (2014A1FC011)