临床口腔医学杂志Issue(12)：714-717,4.DOI:10.3969/j.issn.1003-1634.2015.12.003
糖尿病大鼠菌状乳头及味孔的超微结构研究
Ultrastructural studies on fungiform papillaes and taste pores of diabetic rats
摘要
Abstract
Objective:To observe the ultrastructural alterations of fungiform papillaes and taste pore of type 1 diabetic rats,and to explore the relationship between diabetes and taste damage from the morphology. Method:20 healthy male SD rats were randomly divided into control group(A) and diabetic group(B).Type 1 diabetic rats were induced by a single in-traperitoneal injection streptozotocin(60 mg/kg). And then rats were fed on regular chow diet for 12 weeks.The tongue tis-sues were removed at 12 weeks. And scanning electron microscope was used to observe ultrastructural alterations of fungi-form papillae and taste buds. Result:The number of taste pores was significantly decreased while the number of poreless papillae of experimental fungiform papillae was significantly increased compared with control group.Both the taste pore diam-eter and the area of the taste pores decreased significantly (P <0.001). Conclusion:Diabetes lead to a series of atrophy changes in receptor.The size and number of fungiform papillae taste pore were closely associated with taste sensitivity.关键词
糖尿病大鼠/菌状乳头/味孔/超微结构Key words
diabetic rats/fungiform papillaes/taste pore/ultrastructural分类
医药卫生引用本文复制引用
刘彩云,孙剑,董红,龙明生,庞光明,孟杨..糖尿病大鼠菌状乳头及味孔的超微结构研究[J].临床口腔医学杂志,2015,(12):714-717,4.基金项目
湖北省卫生厅科研基金资助项目（JX1B068）十堰市科技局引导型资助项目 （）
