摘要
Abstract
Objective To investigate the clinical significance on expression of NMP22,CA19-9 and CEA in bladder cancer. Methods Collected 72 cases of bladder cancer and 10 cases of non-bladder cancer, using immunohistochemistry to detect the expression of NMP22,CA19-9 and CEA in bladder cancer and non-bladder cancer tissues,it was analyzed the relationship between their expression in bladder cancer and pathology classification and clinical stage. Results NMP22,CA19-9 and CEA expression in bladder cancer tissues were significantly higher than that of non-bladder cancer.NMP22 expression in bladder cancer tissue was positively correlated with pathology classification and tumor size,but no correlation with clinical stage.NMP22 expression in bladder cancer was negatively correlated with age.CA19-9 expression in bladder cancer tissue was negatively correlated with pathology classification and clinical stage.CEA expression in bladder cancer tissues was positively correlated with pathology classification,clinical stage,and tumor size. Conclusion The delection of NMP22,CA19-9 and CEA,have important role of early diagnosis and monitoring of postoperative recurrence in bladder cancer,it can make more accurate judgement on the biological characteristics of bladder cancer,and provide more sufficient evidence for choice of clinical treatment and prognosis judgement.关键词
膀胱癌/NMP22/CA19-9/CEA/免疫组织化学Key words
bladder cancer/NMP22/CA19-9/CEA/immunohistochemistry分类
医药卫生
