国际眼科杂志Issue(1)：91-93,3.DOI:10.3980/j.issn.1672-5123.2016.1.24
糖化血红蛋白水平对糖尿病患者白内障术后黄斑区视网膜厚度的影响
Effect of HbA1c for macular retinal thickness after phacoemulsification in diabetic patients
摘要
Abstract
AIM: To investigate the infIuence of gIycosyIated hemogIobin ( HbA1c) IeveIs on macuIar retinaI thickness after phacoemuIsification in diabetic patients. METHODS: one hundred and twenty one patients ( 160 eyes ) underwent phacoemuIsification were divided into normaI controI group ( 40 patients with 50 eyes ) and diabetic group ( 81 cases with 110 eyes ) . The patients in the diabetic group was divided into two subgroups, Iow HbA1c group ( HbA1c≤7. 0%) and high HbA1c group (HbA1c>7. 0%). AII patients underwent opticaI coherence tomography (OCT) before and 1mo after cataract surgery to check foveaI retinaI thickness and totaI macuIar voIume. The reIation between HbA1c IeveIs and macuIar retinaI thickness was anaIyzed. RESULTS: FoveaI retinaI thickness before and at 1mo after cataract surgery in patients with diabetes were thicker, compared with normaI controI group, and the difference was statisticaIIy significant (P<0. 05). FoveaI retinaI thickness and totaI macuIar voIume before and at 1mo after surgery in high HbA1c group were thicker than those in Iow HbA1c group, and differences were statisticaIIy significant (P<0. 05). FoveaI retinaI thickness before and at 1mo after surgery in Iow HbA1c group was thicker than those in normaI controI group, but the differences was not statisticaIIy significant ( P>0. 05 ). HbA1c and preoperative foveaI retinaI thickness (r=0. 254, P<0. 01), preoperative totaI macuIar voIume (r=0. 276, P<0. 01), postoperative foveaI retinaI thickness (r=0. 349, P<0.01), postoperative totaI macuIar voIume (r=0. 286, P<0. 01) were positiveIy correIated. CONCLUSION: HbA1c and diabetic macuIar thickness after cataract surgery were positiveIy correIated. If preoperative HbA1c is higher than 7. 0% in diabetic patients with cataract, macuIar thickness shouId be activeIy foIIowed up and giuen timeIy intervention, in order to protect visuaI function.关键词
白内障/糖化血红蛋白/糖尿病/黄斑中心凹视网膜厚度Key words
cataract/gIycosyIated hemogIobin/diabetes/foveaI retinaI thickness引用本文复制引用
钱锦,忽俊,朱蓓菁,陆豪,唐建明..糖化血红蛋白水平对糖尿病患者白内障术后黄斑区视网膜厚度的影响[J].国际眼科杂志,2016,(1):91-93,3.基金项目
上海市卫生局青年课题资助项目(No.20124Y026) （No.20124Y026）
上海市宝山区科学技术委员会课题资助项目(No.12-E-19)@@@@Youth Project of Shanghai Public Health Bureau ( No.20124Y026) （No.12-E-19）
Project Supported by Scientific and Technological Committee of Baoshan District Shanghai(No.12-E-19) （No.12-E-19）
