陕西中医Issue(12):1584-1586,3.DOI:10.3969/j.issn.1000-7369.2015.12.007
晚期肺癌不同中医证型化疗后骨髓抑制规律性的研究
The correlation study of TCM symdrom and myelosuppression after chemotherapy in advanced NSCLC
摘要
Abstract
Objective:To observe the correlation of TCM symdrom and myelosuppression after chemotherapy in advanced NSCLC .Methods:A total of 145 naive patients with advanced NSCLC were accepeted TCM syndrome differen‐tiation and the first line platinum‐based chemotherapy .The four groups of different TCM syndrome were compared the rate and type of myelosuppression after chemotherapy .Results :The incidence of myelosuppression in group with phlegm‐dampness due to deficiency of qi syndrome was 32 .6% ,significant difference between group with yin‐deficiency and toxic‐stasis syndrome (44% ) and group with deficiency of both qi and yin syndrome (43 .6% ) ,dramatic significant difference between group with qi stagnation and blood stasis syndrome (57 .1% ) .Leukopenia was primary in group with phlegm‐dampness due to deficiency of qi syndrome and group with qi stagnation and blood stasis syndrome ,while anemia was pri‐mary in group with yin‐deficiency and toxic‐stasis syndrome and group with deficiency of both qi and yin syndrome .Con‐clusion :The TCM symdrom was related to myelosuppression after chemotherapy in advanced NSCLC .Group with qi stagnation and blood stasis syndrome had more myelosuppression than other TCM syndrome groups .关键词
肺肿瘤/化疗反应/证候Key words
Lung neoplasms/Chemotherapy side-effects/Symptom complex分类
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刘丽荣,张海波,张馥丽,朱燕娟..晚期肺癌不同中医证型化疗后骨髓抑制规律性的研究[J].陕西中医,2015,(12):1584-1586,3.