实用医学杂志2015，Vol.31Issue(23)：3853-3856,4.DOI:10.3969/j.issn.1006-5725.2015.23.011
ADIPOQ基因11377C/G位点多态性与身体活动对儿童代谢综合征的影响
Effect of interaction between ADIPOQ gene 11377C/G polymorphism and physical activity on metabolic syndrome in children
摘要
Abstract
Objectve To study the effect of interaction between ADIPOQ 11377C/G (rs266729) gene polymorphism and physical activity in metabolic syndrome in children. Methods We conducted a case-control study in 114 cases and 114 controls. The genotype of ADIPOQ 11377C/G had been detected in direct sequenc-ing. The effect of interaction between gene polymorphism and physical activity was evaluated by a crossover analysis. Results Efficient physical activity was a protective factor (OR = 0.14); there was interaction between inefficient physical activity and CC genotype of 11377C/G which was a risk factor for metabolic syndrome in children. Conclusion Efficient physical activity can reduce the risk of metabolic syndrome in children. There was interaction between 11377C/G (rs266729) polymorphism and physical activity.关键词
代谢综合征/基因多态性/身体活动/交互作用Key words
Metabolic syndrome/Gene polymorphism/Physical activity/Interaction引用本文复制引用
王凯风,叶萍,王丹,吴柳风,刘伟佳,陈清,李建栋..ADIPOQ基因11377C/G位点多态性与身体活动对儿童代谢综合征的影响[J].实用医学杂志,2015,31(23):3853-3856,4.基金项目
2013年度广东省医学科研基金(编号:A2013358) （编号:A2013358）
