MiRNAs与EGFR-TKIs继发性耐药机制的研究进展OA北大核心CSCDCSTPCDMEDLINE
Advanced Research on MicroRNAs and EGFR-TKIs Secondary Resistance
肺癌是癌症致死率最高的疾病，关于这个疾病的发生机制已得到部分阐明，其中表皮生长因子受体（epidermal growth factor receptor, EGFR）信号通路研究最为深入，在肺癌的发生中起着至关重要的作用。而有效地抑制EGFR信号通路的药物已用于非小细胞肺癌（non-small cell lung cancer, NSCLC）的靶向治疗中，伴有EGFR基因突变的患者使用EGFR酪氨酸激酶抑制剂（EGFR-tyrosine kina…查看全部>>
Lung cancer is a leading cause of cancer mortality worldwide. Several molecular pathways underlying mechanisms of this disease have been partly elucidated, among which the epidermal growth factor receptor (EGFR) pathway is one of the well-known signaling cascades that plays a critical role in tumorigenesis. hTe strategies to effectively inhibit EGFR signaling pathway have been used in non-small cell lung cancer (NSCLC) targeted therapy. Patients withEG…查看全部>>
王明;孙震宇;黄礼年
233000蚌埠，蚌埠医学院 233000蚌埠，蚌埠医学院第一附属医院呼吸与危重症学科233000蚌埠，蚌埠医学院
肺肿瘤MiRNAsEGFR-TKIs继发性耐药
Lung neoplasmsMiRNAsEGFR-TKIsSecondary resistance
《中国肺癌杂志》 2015 (12)
758-763,6
本研究受安徽省教育厅自然科学重点项目（No.KJ2014A158）资助
评论