中国临床药理学杂志Issue(23)：2362-2365,4.DOI:10.13699/j.cnki.1001-6821.2015.23.028
新德里金属β内酰胺酶－1型超级细菌的研究及防控
Study and prevention of NDM-1-producing superbug
欧尾妹 1吕媛1
作者信息
- 1. 北京大学 第一医院 临床药理研究所，北京100191
- 折叠
摘要
Abstract
New Delhi metallo-β-lactamase 1 ( NDM-1 ) belongs to B1 subgroup of metallo-β-lactamase.It can hydrolyze almost all β-lactam antimicrobials (except aztreonam).Most of blaNDM-1 gene was on plasmids, which can easily result in horizontal transmission.There are mainly three ways for human to acquire NDM-1 -producing bacteria, which are nosocomial infection, personal travel and community acquisi-tion.The detection methods of NDM-1 are phenotype screening, pheno-type confirmation and gene confirmation. This review summarized the epidemiology, molecular -biological characteristics, detection methods and prevention measures of NDM -1 -producing bacteria, aiming at enhancing the recognization, prevention and control of NDM -1 -producing superbug.关键词
超级细菌/新德里金属β内酰胺酶-1/金属β内酰胺酶/碳青霉烯类Key words
superbug/New Delhi metallo-β-lactamase 1/metallo-β-lactamase/carbapenem分类
医药卫生引用本文复制引用
欧尾妹,吕媛..新德里金属β内酰胺酶－1型超级细菌的研究及防控[J].中国临床药理学杂志,2015,(23):2362-2365,4.
