中国临床药理学杂志2016，Vol.32Issue(1)：12-14,3.DOI:10.13699/j.cnki.1001-6821.2016.01.004
羟苯磺酸钙联合血栓通对糖尿病视网膜病变致患者视野缺损的临床疗效
Efficacy of calcium dobesilate combined with Xueshuantong on patients with visual field defect induced by diabetic retinopathy
摘要
Abstract
Objective To evaluate the clinical efficacy of calcium dobe-silate combined with Xueshuantong on visual field defects caused by dia-betic retinopathy ( DR ) in patients.Methods A total of 346 patients with DR were divided into treatment group (173 cases) and control group (173 cases).Control group was given Xueshuantong 1.5 g, tid, treat-ment group was treated with dobesilate calcium 0.5 g, tid, on the basis of control group.The total course of the two groups was six months .The clinical efficacy , hemangioma , macular thickness and bleeding spots , vi-sion acuity , vision gray value , within 30 °threshold sensitivity improve-ment, blood, liver and kidney function of the two groups were observed . Results After treatment, the total effective rate of treatment group ( 95.95%) was significantly higher than that in control group ( 78.03%, P<0.05).The hemangioma, macular thickness and bleeding spots im-provement in treatment group were better than those in control group (P<0.05).Visual acuity, vision gray value and within 30°threshold sensitivity improvement in treatment group were better than those in con-trol group ( P<0.05 ) .The blood , liver and kidney function of the two groups had no significant difference ( P>0.05 ) .Conclusion For the treatment of diabetic retinopathy , calcium dobesilate combined with Xushuangtong can significantly improve the clinical symptoms , and had good clinical effect with high safety .关键词
羟苯磺酸钙/血栓通/糖尿病视网膜病变/视野缺损Key words
dobesilate calcium/Xueshuantong/diabetic retinopathy/field defect分类
医药卫生引用本文复制引用
温积权,曹永葆,汪怿,杨杰,刘健,吴若欣,吴小娜,张佳..羟苯磺酸钙联合血栓通对糖尿病视网膜病变致患者视野缺损的临床疗效[J].中国临床药理学杂志,2016,32(1):12-14,3.基金项目
温州市科技计划基金资助项目(Y20140396) （Y20140396）
